PC-TraFF_Professional

Potentially collaborating transcription factor finder

Welcome to PC-TraFF Server

PC-TraFF Service

Results

Your Data

Your Job id:	Sample
Selected database:	hg19
Upstream region:	1000 bp
Downstream region:	100 bp
Minimal distance between pairs:	5
Maximum distance between pairs:	20
Z-Score:	3
Email:

PC-TraFF

Applying our method to your data set,we observed 63 PC-TraFF significant collaborating TFBS pairs. The importance of 39 pairs out of all significant pairs has been experimentally verified by previous studies regarding their interactions which are summarized in TRANSCompel and BioGRID interaction databases. The remaining 24 TFBS pairs found by PC-TraFF have not been experimentally validated yet and the reason for their significance is still unclear. But they could provide new hypotheses for further experimental validation.

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Predicted collaboration network of PC-TraFF significant TFBS pairs: Blue lines denote interactions between TFs whose importance is experimentally verified whereas red lines indicate potential interactions between transcription factors that have not been experimentally validated yet.

Download Results

For more detail and clustering of the collaboration network:

PC-TraFF Significant Pairs

Pairs

Z-Score

Reference

V$EGR_Q6 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$SP1_Q2_01		SP1, SP2, SP3, SP4

6.61109

BioGRID

V$CETS1P54_01 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$SP1_Q2_01		SP1, SP2, SP3, SP4

5.74079

TRANSCompel

V$MYCMAX_B - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$SP1_Q2_01		SP1, SP2, SP3, SP4

5.45322

BioGRID

V$SP1_Q4_01 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q4_01		SP1, SP2, SP3, SP4
V$SP1_Q2_01		SP1, SP2, SP3, SP4

5.16719

TRANSCompel, BioGRID

V$SP1_Q6 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q6		SP1, SP3, SP4
V$SP1_Q2_01		SP1, SP2, SP3, SP4

4.98436

TRANSCompel, BioGRID

V$CETS1P54_01 - V$EGR_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$EGR_Q6		EGR1, EGR2, EGR3

4.83617

V$CETS1P54_01 - V$NFKB_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$NFKB_Q6		NFKB1, NFKB2, RELA

4.70068

TRANSCompel

V$CEBP_Q2 - V$STAT6_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CEBP_Q2		CEBPA, CEBPB, CEBPD, CEBPE, CEBPG
V$STAT6_01		STAT6

4.68172

TRANSCompel, BioGRID

V$CETS1P54_01 - V$PEBP_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$PEBP_Q6		CBFB, RUNX1, RUNX2, RUNX3

4.61397

BioGRID

V$AP1_Q2_01 - V$AP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$AP1_Q2_01		FOS, FOSB, FOSL1, FOSL2, JUN
V$AP1_Q4_01		FOS, FOSB, FOSL1, FOSL2, JUN

4.59329

TRANSCompel, BioGRID

V$CETS1P54_01 - V$MYCMAX_B (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$MYCMAX_B		MAX, MYC

4.55094

V$SP1_Q2_01 - V$PEBP_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q2_01		SP1, SP2, SP3, SP4
V$PEBP_Q6		CBFB, RUNX1, RUNX2, RUNX3

4.48099

V$E2F_Q3_01 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$E2F_Q3_01		E2F1, E2F3, E2F4, TFDP1
V$SP1_Q2_01		SP1, SP2, SP3, SP4

4.47101

TRANSCompel, BioGRID

V$CEBPB_02 - V$STAT6_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CEBPB_02		CEBPB
V$STAT6_01		STAT6

4.42431

TRANSCompel

V$MYCMAX_B - V$EGR_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$EGR_Q6		EGR1, EGR2, EGR3

4.37014

V$PU1_Q6 - V$ETS_Q4 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$PU1_Q6		SPI1
V$ETS_Q4		ELF1, ELF2, ELK1, ELK4, ERF, ERG, ETS1, ETS2, ETV7, FLI1

4.36274

TRANSCompel, BioGRID

V$EGR_Q6 - V$SP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$SP1_Q4_01		SP1, SP2, SP3, SP4

4.24721

BioGRID

V$SP1_Q2_01 - V$KROX_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q2_01		SP1, SP2, SP3, SP4
V$KROX_Q6		EGR1, EGR2, EGR3, EGR4

4.23477

BioGRID

V$NFKB_Q6 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$NFKB_Q6		NFKB1, NFKB2, RELA
V$SP1_Q2_01		SP1, SP2, SP3, SP4

4.21052

TRANSCompel, BioGRID

V$SP1_Q6 - V$EGR_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q6		SP1, SP3, SP4
V$EGR_Q6		EGR1, EGR2, EGR3

4.16624

BioGRID

V$MYCMAX_B - V$E2F_Q3_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$E2F_Q3_01		E2F1, E2F3, E2F4, TFDP1

4.14488

TRANSCompel

V$MYCMAX_B - V$AHRHIF_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$AHRHIF_Q6		AHR, AHRR, ARNT, ARNT2, HIF1A

4.07671

BioGRID

V$CETS1P54_01 - V$SP1_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$SP1_Q6		SP1, SP3, SP4

4.07242

TRANSCompel

V$CETS1P54_01 - V$SP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$SP1_Q4_01		SP1, SP2, SP3, SP4

4.07225

TRANSCompel

V$STAT6_01 - V$OCT_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$STAT6_01		STAT6
V$OCT_Q6		POU2AF1, POU2F1, POU2F2, POU2F3, POU3F1, POU3F2, POU3F3, POU4F1

3.95444

V$AP1FJ_Q2 - V$AP1_Q2 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$AP1FJ_Q2		FOS, JUN,
V$AP1_Q2		FOS, FOSB, FOSL1, FOSL2, JUN

3.90675

TRANSCompel, BioGRID

V$SP1_Q6 - V$SP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q6		SP1, SP3, SP4
V$SP1_Q4_01		SP1, SP2, SP3, SP4

3.85297

TRANSCompel, BioGRID

V$SP1_Q2_01 - V$AHRHIF_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q2_01		SP1, SP2, SP3, SP4
V$AHRHIF_Q6		AHR, AHRR, ARNT, ARNT2, HIF1A

3.82345

TRANSCompel, BioGRID

V$SP1_Q6 - V$MYCMAX_B (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q6		SP1, SP3, SP4
V$MYCMAX_B		MAX, MYC

3.79867

BioGRID

V$MYCMAX_B - V$SP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$SP1_Q4_01		SP1, SP2, SP3, SP4

3.76648

BioGRID

V$CETS1P54_01 - V$KROX_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$KROX_Q6		EGR1, EGR2, EGR3, EGR4

3.75463

V$CP2_01 - V$SF1_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CP2_01		TFCP2
V$SF1_Q6		NR5A1

3.71611

V$EGR_Q6 - V$E2F_Q3_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$E2F_Q3_01		E2F1, E2F3, E2F4, TFDP1

3.70569

V$MYCMAX_B - V$PEBP_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$PEBP_Q6		CBFB, RUNX1, RUNX2, RUNX3

3.64847

BioGRID

V$AP1_C - V$AP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$AP1_C		JUN
V$AP1_Q2_01		FOS, FOSB, FOSL1, FOSL2, JUN

3.62346

TRANSCompel, BioGRID

V$EGR_Q6 - V$AHRHIF_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$AHRHIF_Q6		AHR, AHRR, ARNT, ARNT2, HIF1A

3.61633

V$CEBPB_02 - V$CEBP_Q2 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CEBPB_02		CEBPB
V$CEBP_Q2		CEBPA, CEBPB, CEBPD, CEBPE, CEBPG

3.60620

TRANSCompel, BioGRID

V$OCT_Q6 - V$AP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$OCT_Q6		POU2AF1, POU2F1, POU2F2, POU2F3, POU3F1, POU3F2, POU3F3, POU4F1
V$AP1_Q4_01		FOS, FOSB, FOSL1, FOSL2, JUN

3.59412

TRANSCompel

V$SOX9_B1 - V$STAT6_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SOX9_B1		SOX9
V$STAT6_01		STAT6

3.55285

V$CETS1P54_01 - V$SMAD_Q6_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$SMAD_Q6_01		SMAD1, SMAD2, SMAD3, SMAD4

3.52760

TRANSCompel

V$NFKB_Q6 - V$EGR_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$NFKB_Q6		NFKB1, NFKB2, RELA
V$EGR_Q6		EGR1, EGR2, EGR3

3.52732

BioGRID

V$AP1_Q6 - V$AP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$AP1_Q6		FOS, FOSB, FOSL1, FOSL2, JUN
V$AP1_Q4_01		FOS, FOSB, FOSL1, FOSL2, JUN

3.51993

TRANSCompel, BioGRID

V$CETS1P54_01 - V$PU1_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$PU1_Q6		SPI1

3.40952

TRANSCompel, BioGRID

V$SP1_Q2_01 - V$CP2_02 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q2_01		SP1, SP2, SP3, SP4
V$CP2_02		TFCP2

3.40870

V$ELK1_02 - V$CETS1P54_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$ELK1_02		ELK1
V$CETS1P54_01		ETS1

3.40752

V$EGR_Q6 - V$PEBP_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$PEBP_Q6		CBFB, RUNX1, RUNX2, RUNX3

3.39213

V$CP2_01 - V$SP1_Q2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CP2_01		TFCP2
V$SP1_Q2_01		SP1, SP2, SP3, SP4

3.39142

V$EGR_Q6 - V$KROX_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$KROX_Q6		EGR1, EGR2, EGR3, EGR4

3.37921

V$AP1_Q2 - V$AP1_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$AP1_Q2		FOS, FOSB, FOSL1, FOSL2, JUN
V$AP1_Q6		FOS, FOSB, FOSL1, FOSL2, JUN

3.26117

TRANSCompel, BioGRID

V$MYCMAX_B - V$CP2_02 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$CP2_02		TFCP2

3.24504

V$CETS1P54_01 - V$CP2_02 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$CP2_02		TFCP2

3.18113

V$E2F_Q3_01 - V$E2F_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$E2F_Q3_01		E2F1, E2F3, E2F4, TFDP1
V$E2F_Q4_01		E2F1, E2F3, E2F4, TFDP1

3.14993

TRANSCompel, BioGRID

V$MYCMAX_B - V$KROX_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$MYCMAX_B		MAX, MYC
V$KROX_Q6		EGR1, EGR2, EGR3, EGR4

3.14639

V$CETS1P54_01 - V$CP2_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CETS1P54_01		ETS1
V$CP2_01		TFCP2

3.13834

V$CP2_01 - V$EGR_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$CP2_01		TFCP2
V$EGR_Q6		EGR1, EGR2, EGR3

3.12055

V$STAT6_01 - V$AP1_Q4_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$STAT6_01		STAT6
V$AP1_Q4_01		FOS, FOSB, FOSL1, FOSL2, JUN

3.10665

TRANSCompel, BioGRID

V$E2F_Q3_01 - V$AHRHIF_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$E2F_Q3_01		E2F1, E2F3, E2F4, TFDP1
V$AHRHIF_Q6		AHR, AHRR, ARNT, ARNT2, HIF1A

3.08963

V$EGR_Q6 - V$CP2_02 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$EGR_Q6		EGR1, EGR2, EGR3
V$CP2_02		TFCP2

3.08527

V$SP1_Q4_01 - V$PEBP_Q6 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$SP1_Q4_01		SP1, SP2, SP3, SP4
V$PEBP_Q6		CBFB, RUNX1, RUNX2, RUNX3

3.08395

V$STAT6_01 - V$AP1_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$STAT6_01		STAT6
V$AP1_01		FOS, FOSB, FOSL1, JUN, JUNB, JUND

3.07367

TRANSCompel, BioGRID

V$STAT6_01 - V$FOX_Q2 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$STAT6_01		STAT6
V$FOX_Q2		FOXD3, FOXF1, FOXF2, FOXH1, FOXJ1

3.07188

V$NFKB_Q6 - V$MYCMAX_B (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$NFKB_Q6		NFKB1, NFKB2, RELA
V$MYCMAX_B		MAX, MYC

3.04718

BioGRID

V$STAT6_01 - V$IRF_Q6_01 (

)

Pair Information

PWM	Sequence Logo	Linked TFs
V$STAT6_01		STAT6
V$IRF_Q6_01		IRF1, IRF2, IRF3, IRF4, IRF5, IRF7, IRF8, ISGF3G

3.00782

BioGRID